Fierce Hair Growth is an evolution of the discoveries of Growth Factors made by Doctor Stanley Cohen and Doctor Rita Levi-Montalcini, who were jointly awarded with the Nobel Prize in 1986. The discovery of Growth Factors have transformed the viability of hair growth treatments, making them completely natural, fast, effective, scientific, and easy.
History of Growth Factors
Growth Factors were discovered in 1986 by Stanley Cohen. This work to understand and explain their function was so significant that Cohen won a Nobel Prize that same year for his findings. Since the discovery, they have been synthesised for use in clinical medicine and by skin formulators and scientists who were wise enough to recognise their healing potential.
Over the last 20 plus years, growth factors have been used medically to treat blood disease, cancers and assist with wound healing. The medical world has embraced the role of growth factors and is continuing to research growth factors to better utilise them. Through medical research, scientists have been able to identify the key growth factors that facilitate hair growth – those are the very same used in Fierce treatments.
What are growth factors?
Growth factors are protein molecules which are naturally produced within our bodies. Different growth factors do different things through their function to regulate cell division and cell survival. As they bind to receptors on the cell surface, growth factors activate cellular proliferation and/or differentiation.
By scientifically mimicking the growth factors naturally found in the body to produce hair, we are able to stimulate these dormant cells and follicles to start producing hair again. The growth factors used during this treatment are manufactured to over 149 times the concentration of what the body produces naturally, making the treatment incredibly effective. Our body naturally produces 127 ppm (parts per million) of hair growth factors compared to the growth factor we use during the treatments which has 19000 ppm. Rest assured that the growth factors we use are bacteria based, and contain no animal or human factors . The growth factors are freeze dried and stored in a uniquely designed bottle allowing them to keep their original bioactivity level until they are used.
How do Growth Factors Work?
Growth factors are proteins that trigger stem cells to activate. They attach to specific growth factor receptors, then send a message to the nucleus telling it to do something – in this case to grow hair
What Growth Factors do we use?
There are 6 different Growth Factors which we use to encourage hair growth. The 6 growth factors that are used are: Noggin, bFGF, IGF-1, VEGF, SCF & KGF
All 6 of these Growth Factors have a different function however they work together to encourage hair growth and help to prevent further hair loss. The function of each growth factor is:
Noggin (BMP Antagonist)
The 2 major benefits of Noggin are:
- It inhibits BMP (our own growth factor) which stops the destruction of hair follicle. Noggin stops Testosterone from converting into DHT. Noggin also promotes hair growth and stops the depigmentation of hair.
- It strengthens the hair whilst stimulating the hair follicles to produce healthier hair, and also helps the blood circulation in the scalp which revitalises the hair follicles.
bFGF (Basic fibroblast Growth Factor) bFGF helps blood circulation in the scalp and revitalises hair follicles.
IGF-1 (Insulin-like Growth Factor) IGF-1 strengthens hair whilst stimulating the hair follicles to produce a strong hair shaft.
VEGF (Vascular Endothelial Growth Factor) VEGF stimulates hair growth by facilitating the nutrient feeding to the hair follicle. This process is done by VEGF induced angiogenesis (new blood vessels forming from pre-existing vessels).
SCF (Stem Cell Factor) Delivering SCF to the base of the hair follicle, it helps to strengthen hair whilst stimulating the hair follicle to produce a strong hair shaft. This is the growth factor which produces pigment. SCF creates a physiological change in the hair; not giving it a “dye”.
KGF-2 (Keratinocyte Growth Factor) KGF-2 stimulates capillaries and encourages the inner lining of the blood vessels to develop and maintain therefore getting the cells to grow and increase production (endothelial cell migration and proliferation). KGF-2 also encourages quicker growth of follicles.
Additional ingredients include:
Water – to hydrate the cells
37 varieties of nutrients essential for hair follicle metabolism
21 kinds of amino acids which are building blocks for cell renewal
Vitamin B complex to stimulate energy metabolism, absolutely essential for cell reproduction
Glutathione which is a detoxifying agent
Minerals including zinc and magnesium to improve the ion balance
In Summary, Growth Factors:
- Produce stronger hair
- Produce thicker hair
- Increase blood supply to the scalp
- Return pigment/colour to the hair
- Create entirely new hair
- Stop our own Growth Factors from sending signals to the follicle to stop it from growing
The Hamilton scale is used to measure hair loss in both men and women. There are 2 different Hamilton scales used for each sex. When considering the treatment it is very important to remember, if there is no hair follicle there will be no growth. Follicles can be dormant for years and then be revived but there must be a follicle there for the treatments to have any effect. It is graded for 1-7 for men. The treatment is effective on men who fall from 1-5 on the Hamilton scale. We are unable to treat anyone male who falls between 6 and 7 on the Hamilton scale.